n-methylbenzamide|CAS 613-93-4|C8H9NO|Guanlang

Short Description:

Product Name: N-Methylbenzamide

CAS: 613-93-4

Appearance: White Crystalline

 


  • Manufacturer: Hebei Guanlang Biotechnology Co., Ltd.
  • Stock status: In stock
  • Delivery: Within 3 working days
  • Shipping Method: Express,Sea,Air,Special line
  • Product Detail

    Factory information

    Product Tags

     

    We are one of the leading n-methylbenzamide suppliers and manufacturers in china, if you want to find n-methylbenzamide factory, feel free to contact us and drop us a email.

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    1. What’s  N-Methylbenzamide?

     

    N-methylbenzamide is an effective phosphodiesterase 10A (pde10a) inhibitor. N-methylbenzamide has anticancer activity.PDE10A is a recently identified phosphodiesterase with a quite remarkable localization since the protein is abundant only in brain tissue. Based on this unique localization, research has focused extensively on using PDE10A modulators as a novel therapeutic approach for dysfunction in the basal ganglia circuit including Parkinson’s disease, Huntington’s disease, schizophrenia, addiction and obsessive compulsive disorder. Medicinal chemistry efforts identified the N-methyl-N-[4-(quinolin-2-ylmethoxy)-phenyl]-isonicotinamide as a nanomolar PDE10A inhibitor. A subsequent Lead-optimization program identified analogous N-methylanilides and their corresponding N-methylbenzamide as potent PDE10A inhibitors, concurrently some interesting and unexpected binding modes were identified.

     

    613-93-4613-93-4

    Melting point 76-78 ° C

    Boiling point 167 ° C

    Density 1.1031

    Refractive index 1.5589

    Storage conditions sealed dry, room temperature

    Solubility ethanol: soluble 50mg / ml,water solubility:Insoluble in Water

    CAS: 613-93-4

    Appearance: White Crystalline

     

    2. Main application

    Inhibitor, anticancer,organic synthesis intermediate,laboratories chemicals

    3.Storage and Packing

    613-93-4

    3.First aid measures

    Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention.

    Skin Contact: Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes.

    Inhalation: Remove from exposure, lie down. Remove to fresh air. If not breathing, give artificial respiration.

    Ingestion: Clean mouth with water. Get medical attention.

    Most important symptoms and effects: No information available.

    Self-Protection of the First Aider: No special precautions required.

    Notes to Physician: Treat symptomatically.

    4.  Transport information

    Road and Rail Transport : Not Regulated

    IMDG/IMO : Not regulated

    IATA : Not regulated

    Special Precautions for User: No special precautions required

    5. HTML5 spectrum

    N-methylbenzamide


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  • Hebei Guanlang Biotechnology Co., Ltd. belongs to Guanlang Group, which was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector among Beijing Tianjin and Hebei and has advantage of convenient transportation . Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.We have our own factory and lab,also offer customized synthesis service for our customers.