Diltiazem CAS NO: 42399-41-7
|Boiling point||594.4ºC at 760 mmHg|
|Melting point||212 °C|
|Storage condition||Seal and store in a dry place|
Diltiazem Pharmacology and toxicology：
1.This product is a non-dihydropyridine calcium channel blocker. Its effect is related to the inhibition of calcium influx during depolarizing of myocardium and vascular smooth muscle.
2.This product can effectively dilate the epicardial and subendocardial coronary arteries, relieve spontaneous angina or angina caused by ergoxin induced coronary artery spasm; Reduces myocardial oxygen demand, increases exercise tolerance, and relieves exertional angina by slowing the heart rate and lowering blood pressure.
3.This product relaxes the vascular smooth muscle, decreases the peripheral vascular resistance and lowers the blood pressure. The extent of hypotension is related to the degree of hypertension, and the normal blood pressure only makes the blood pressure drop slightly.
4.This product has negative inotropic effect and can slow down the conduction of sinoatrial node and atrioventricular node.
This product is a calcium channel blocker, which can relieve angina pectoris, reduce blood pressure, have negative inotropic effect, and slow down the conduction of sinoatrial node and atrioventricular node.
Diltiazem is a new type of calcium antagonist, which can be used to treat supraventricular dysrhythmia, angina pectoris and hypertension in the elderly.
Used for treatment of hypertensive Patients.
1.Allergic to Diltiazem or other calcium channel blockers.
2.Severe hypotension or cardiogenic shock.
3.Acute myocardial infarction with pulmonary congestion.
4.Contraindicated in pregnancy
Diltiazem Adverse reaction:
Common: edema, headache, nausea, dizziness, rash, weakness
Diltiazem Packaging and Shipping：
Packaging: 1kg/Aluminum Foil Bag, 25kg/drum
Shipping: 7-15 days for big orders
Diltiazem Sample order