Good quality Tablet Excipients - n-methylbenzamide|CAS 613-93-4|C8H9NO|Guanlang – Guanlang Detail:
We are one of the leading n-methylbenzamide suppliers and manufacturers in china, if you want to find n-methylbenzamide factory, feel free to contact us and drop us a email.
1. What’s N-Methylbenzamide?
N-methylbenzamide is an effective phosphodiesterase 10A (pde10a) inhibitor. N-methylbenzamide has anticancer activity.PDE10A is a recently identified phosphodiesterase with a quite remarkable localization since the protein is abundant only in brain tissue. Based on this unique localization, research has focused extensively on using PDE10A modulators as a novel therapeutic approach for dysfunction in the basal ganglia circuit including Parkinson’s disease, Huntington’s disease, schizophrenia, addiction and obsessive compulsive disorder. Medicinal chemistry efforts identified the N-methyl-N-[4-(quinolin-2-ylmethoxy)-phenyl]-isonicotinamide as a nanomolar PDE10A inhibitor. A subsequent Lead-optimization program identified analogous N-methylanilides and their corresponding N-methylbenzamide as potent PDE10A inhibitors, concurrently some interesting and unexpected binding modes were identified.
Melting point 76-78 ° C
Boiling point 167 ° C
Density 1.1031
Refractive index 1.5589
Storage conditions sealed dry, room temperature
Solubility ethanol: soluble 50mg / ml,water solubility:Insoluble in Water
CAS: 613-93-4
Appearance: White Crystalline
2. Main application
Inhibitor, anticancer,organic synthesis intermediate,laboratories chemicals
3.Storage and Packing
3.First aid measures
Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention.
Skin Contact: Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes.
Inhalation: Remove from exposure, lie down. Remove to fresh air. If not breathing, give artificial respiration.
Ingestion: Clean mouth with water. Get medical attention.
Most important symptoms and effects: No information available.
Self-Protection of the First Aider: No special precautions required.
Notes to Physician: Treat symptomatically.
4. Transport information
Road and Rail Transport : Not Regulated
IMDG/IMO : Not regulated
IATA : Not regulated
Special Precautions for User: No special precautions required
5. HTML5 spectrum
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Cooperation
We are experienced manufacturer. Wining the majority of the crucial certifications of its market for Good quality Tablet Excipients - n-methylbenzamide|CAS 613-93-4|C8H9NO|Guanlang – Guanlang, The product will supply to all over the world, such as: Czech, Brunei, Seattle, During the 10 years of operating, our company always try our best to bring consumption satisfaction for user, built a brand name for ourselves and a solid position in the international market with major partners come from many countries such as Germany, Israel, Ukraine, United Kingdom, Italy, Argentina, France, Brazil, and so on. Last but not least, price of our products are very suitable and have fairly high competition with other companies.
Hebei Guanlang Biotechnology Co., Ltd. belongs to Guanlang Group, which was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector among Beijing Tianjin and Hebei and has advantage of convenient transportation . Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.We have our own factory and lab,also offer customized synthesis service for our customers.
By Matthew Tobias from Zimbabwe - 2018.02.21 12:14
This supplier's raw material quality is stable and reliable, has always been in accordance with the requirements of our company to provide the goods that quality meet our requirements.
By Maria from South Africa - 2018.06.26 19:27
