Factory wholesale Intermediate Pharma - n-methylbenzamide|CAS 613-93-4|C8H9NO|Guanlang – Guanlang Detail:
We are one of the leading n-methylbenzamide suppliers and manufacturers in china, if you want to find n-methylbenzamide factory, feel free to contact us and drop us a email.
1. What’s N-Methylbenzamide?
N-methylbenzamide is an effective phosphodiesterase 10A (pde10a) inhibitor. N-methylbenzamide has anticancer activity.PDE10A is a recently identified phosphodiesterase with a quite remarkable localization since the protein is abundant only in brain tissue. Based on this unique localization, research has focused extensively on using PDE10A modulators as a novel therapeutic approach for dysfunction in the basal ganglia circuit including Parkinson’s disease, Huntington’s disease, schizophrenia, addiction and obsessive compulsive disorder. Medicinal chemistry efforts identified the N-methyl-N-[4-(quinolin-2-ylmethoxy)-phenyl]-isonicotinamide as a nanomolar PDE10A inhibitor. A subsequent Lead-optimization program identified analogous N-methylanilides and their corresponding N-methylbenzamide as potent PDE10A inhibitors, concurrently some interesting and unexpected binding modes were identified.
Melting point 76-78 ° C
Boiling point 167 ° C
Density 1.1031
Refractive index 1.5589
Storage conditions sealed dry, room temperature
Solubility ethanol: soluble 50mg / ml,water solubility:Insoluble in Water
CAS: 613-93-4
Appearance: White Crystalline
2. Main application
Inhibitor, anticancer,organic synthesis intermediate,laboratories chemicals
3.Storage and Packing
3.First aid measures
Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention.
Skin Contact: Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes.
Inhalation: Remove from exposure, lie down. Remove to fresh air. If not breathing, give artificial respiration.
Ingestion: Clean mouth with water. Get medical attention.
Most important symptoms and effects: No information available.
Self-Protection of the First Aider: No special precautions required.
Notes to Physician: Treat symptomatically.
4. Transport information
Road and Rail Transport : Not Regulated
IMDG/IMO : Not regulated
IATA : Not regulated
Special Precautions for User: No special precautions required
5. HTML5 spectrum
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Cooperation
Our advancement depends on the superior gear ,superb talents and consistently strengthened technology forces for Factory wholesale Intermediate Pharma - n-methylbenzamide|CAS 613-93-4|C8H9NO|Guanlang – Guanlang, The product will supply to all over the world, such as: Norway, Algeria, Sri Lanka, Our products are very popular in the word, like South American, Africa, Asia and so on. Companies to "create first-class products" as the goal, and strive to deliver customers with high quality solutions, present high-quality after-sales service and technical support, and customer mutual benefit, create a better career and future!
Hebei Guanlang Biotechnology Co., Ltd. belongs to Guanlang Group, which was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector among Beijing Tianjin and Hebei and has advantage of convenient transportation . Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.We have our own factory and lab,also offer customized synthesis service for our customers.
By Michaelia from Brisbane - 2018.10.31 10:02
A good manufacturers, we have cooperated twice, good quality and good service attitude.
By Alex from Yemen - 2018.12.14 15:26
