Bottom price Pharma Intermediates - Triphosgene CAS 32315-10-9 – Guanlang Detail:
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Product Name: Triphosgene ( Triphosgen; triphosgene; bis(trichloromethyl) carbonate; carbonic acid bistrichlor methyl ester; bis-(trichloromethyl)-carbonat; methanol, trichloro-, carbonate (2:1); btc)
CAS No.: 32315-10-9
Molecular Fomula: C3Cl6O3
Molecular weight: 296.75
Appearance: white crystal
Triphosgene Typical Properties
| Item | Specifications |
| Appearance | White crystal |
| Assay % | ≥99.5 |
| Melting point (ºC) | 79-81 |
| Loss on drying % | ≤0.5 |
| Ignition residue % | ≤0.1 |
Triphosgene Usage
As a substitute product of the highly toxic phosgene and diphosgene in the synthesis, the product has low toxicity, safe and convenient use, mild reaction conditions, good selectivity and high yield.
For the synthesis of chloroformate, isocyanate, polycarbonate and acid chloride,Various isocyanates can be prepared by carbonylation of phosgene with primary amine, but side reactions often occur because phosgene is difficult to measure accurately. Triphosgene is a solid, which can be measured accurately, and triphosgene is used to replace phosgene, which greatly improves its safety, so it can safely replace phosgene. The reaction of Triphosgene with amine compounds is a widely used field. The reaction has strong selectivity. Some functional groups do not need protection, and can directly produce isocyanates, urea and other compounds. Various isocyanates can be synthesized by carbonylation reaction of Triphosgene and various primary amines. The target product can be obtained by accurately controlling the ratio of Triphosgene and amine without by-products. For example, 2,4-dimethyldiisocyanate (TDI) can be synthesized by the reaction of Triphosgene with chemical book 2,4-Diaminotoluene; Triphosgene reacts with 4,4 ‘- diaminodiphenylmethane to produce 4,4′ – diphenylmethane diisocyanate (MDI); Sodium hexamethylene diisocyanate (HDI) can be produced by triphosgene and hexamethylene diamine. In the carbonylation reaction of BTC, cyclization condensation reaction can also be carried out. Triphosgene is widely used in this kind of reaction, which can be used to prepare n-carbonyl anhydride, various important heterocyclic compounds and cyclic carbonate compounds. The former can be used to prepare active amino acids and polypeptide compounds, and the latter can be used to prepare various pharmaceutical and pesticide intermediates.
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Bear "Customer 1st, Good quality first" in mind, we work closely with our prospects and supply them with efficient and professional services for Bottom price Pharma Intermediates - Triphosgene CAS 32315-10-9 – Guanlang, The product will supply to all over the world, such as: Slovakia, Oslo, Norway, With a wide range, good quality, reasonable prices and stylish designs, our products are extensively used in public placesand other industries. Our products are widely recognized and trusted by users and can meet continuously developing economic and social needs. We welcome new and old customers from all walks of life to contact us for future business relationships and achieving mutual success!
Hebei Guanlang Biotechnology Co., Ltd. belongs to Guanlang Group, which was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector among Beijing Tianjin and Hebei and has advantage of convenient transportation . Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.We have our own factory and lab,also offer customized synthesis service for our customers.
By Michelle from Spain - 2017.04.28 15:45
The supplier abide the theory of "quality the basic, trust the first and management the advanced" so that they can ensure a reliable product quality and stable customers.
By Elizabeth from US - 2017.08.18 18:38
