18 Years Factory Talc Glidant - n-methylbenzamide|CAS 613-93-4|C8H9NO|Guanlang – Guanlang

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18 Years Factory Talc Glidant - n-methylbenzamide|CAS 613-93-4|C8H9NO|Guanlang – Guanlang Detail:

We are one of the leading n-methylbenzamide suppliers and manufacturers in china, if you want to find n-methylbenzamide factory, feel free to contact us and drop us a email.

1. What’s N-Methylbenzamide?

N-methylbenzamide is an effective phosphodiesterase 10A (pde10a) inhibitor. N-methylbenzamide has anticancer activity.PDE10A is a recently identified phosphodiesterase with a quite remarkable localization since the protein is abundant only in brain tissue. Based on this unique localization, research has focused extensively on using PDE10A modulators as a novel therapeutic approach for dysfunction in the basal ganglia circuit including Parkinson’s disease, Huntington’s disease, schizophrenia, addiction and obsessive compulsive disorder. Medicinal chemistry efforts identified the N-methyl-N-[4-(quinolin-2-ylmethoxy)-phenyl]-isonicotinamide as a nanomolar PDE10A inhibitor. A subsequent Lead-optimization program identified analogous N-methylanilides and their corresponding N-methylbenzamide as potent PDE10A inhibitors, concurrently some interesting and unexpected binding modes were identified.

Melting point 76-78 ° C

Boiling point 167 ° C

Density 1.1031

Refractive index 1.5589

Storage conditions sealed dry, room temperature

Solubility ethanol: soluble 50mg / ml,water solubility:Insoluble in Water

CAS: 613-93-4

Appearance: White Crystalline

2. Main application

Inhibitor, anticancer,organic synthesis intermediate,laboratories chemicals

3.Storage and Packing

3.First aid measures

Eye Contact: Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Get medical attention.

Skin Contact: Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes.

Inhalation: Remove from exposure, lie down. Remove to fresh air. If not breathing, give artificial respiration.

Ingestion: Clean mouth with water. Get medical attention.

Most important symptoms and effects: No information available.

Self-Protection of the First Aider: No special precautions required.

Notes to Physician: Treat symptomatically.

4. Transport information

Road and Rail Transport : Not Regulated

IMDG/IMO : Not regulated

IATA : Not regulated

Special Precautions for User: No special precautions required

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We insist on offering high-quality production with great enterprise concept, honest product sales and also the finest and fast service. it will bring you not only the superior quality solution and huge profit, but the most significant should be to occupy the endless market for 18 Years Factory Talc Glidant - n-methylbenzamide|CAS 613-93-4|C8H9NO|Guanlang – Guanlang, The product will supply to all over the world, such as: Kuwait, Swaziland, Sheffield, Our company has built stable business relationships with many well-known domestic companies as well as oversea customers. With the goal of providing high quality products to customers at low cots, we are committed to improving its capacities in research, development, manufacturing and management. We have honored to receive recognition from our customers. Till now we have passed ISO9001 in 2005 and ISO/TS16949 in 2008. Enterprises of "quality of survival, the credibility of development" for the purpose, sincerely welcome domestic and foreign businessmen to visit to discuss cooperation.

Hebei Guanlang Biotechnology Co., Ltd. belongs to Guanlang Group, which was founded in 2007 , located in Shijiazhuang city which is the capital of Hebei Province and hub sector among Beijing Tianjin and Hebei and has advantage of convenient transportation . Our company is a modern high-tech chemical enterprise with Research & Development, production and sales.We have our own factory and lab,also offer customized synthesis service for our customers.

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The manufacturer gave us a big discount under the premise of ensuring the quality of products, thank you very much, we will select this company again.