Colorless or white rhombic crystalline powder. No odor, slightly bitter taste, after the sense of anesthesia. Change color in the light. Insoluble in water, slightly soluble in fat oil, soluble in dilute acid, ethanol, ether, chloroform, almond oil, olive oil.Used as a local anesthetic. Long – term effect, low toxicity. It is mainly used for relieving pain of skin diseases, trauma, hemorrhoids and ulcer. Some condom companies add benzocaine to condoms to slow men’s ejaculation during sex.
Benzocaine, sold under the brand name Orajel among others, is an ester local anesthetic commonly used as a topical pain reliever or in cough drops. It is the active ingredient in many over-the-counter anesthetic ointments such as products for oral ulcers. It is also combined with antipyrine to form A/B otic drops to relieve ear pain and remove earwax.
Benzocaine is a local anesthetic (numbing medication). It works by blocking nerve signals in your body.
2)Application of benzocaine
Benzocaine topical is used to reduce pain or discomfort caused by minor skin irritations, sore throat, sunburn, vaginal or rectal irritation, ingrown toenails, hemorrhoids, and many other sources of minor pain on a surface of the body. Benzocaine is also used to numb the skin or surfaces inside the mouth, nose, throat, vagina, or rectum to lessen the pain of inserting a medical instrument such as a tube or speculum.
Benzocaine topical should not be used to treat teething pain in infants, and is not approved for use in a child younger than 2 years old. There are many brands and forms of benzocaine topical available. Not all brands are listed on this leaflet.|
Benzocaine topical may also be used for purposes not listed in this medication guide.
3)COA of benzocaine
|Test Items||Specification||Test Results|
|Appearance||White crystals or a white crystalline powder||Conform|
|Identification||ABE. It appears positive reaction|
|Appearance of solution||Clear and colourless||Conform|
|Loss on drying||≤0.5%||0.07%|
|Assay ( on dry basis )||99.0-101.0%||99.87%|
|Conclusion||Conform to BP200|